Body temperature discusses the importance of maintaining a proper body temperature within rodents during experimental procedures. The applicability of an electronic monitoring system using microchip transponders for measurement of body temperatures was tested in 6 week old conventional danish weaners infected with classical swine fever virus csfv. Monitoring animals for pain and distress is effective when a. 1 cutaneous heat loss is a function of mean skin and ambient temperatures. Which statement is true about supporting body temperature in anesthetized rodents. Body temperature is a basic physiological parameter which is often measured in awake rodents by rectal probe thermometry lomax 1966while it is known that rectal probe measurements are less accurate and less reliable than other methods that involve surgical implantation of temperature recording devices dallman et al 2006 the procedure also results in long lasting.
The treatment regimen for painful rodents should be based on the source of the pain and may include opiates nsaids or other analgesic agents. 2 central thermoregulatory control is determined by a combination of core and mean skin temperatures. During the procedure mice should be monitored mainly for anesthesia body temperature and cardiovascular and respiratory function. Which statement is true regarding care procedures for mice undergoing surgery. Subcutaneous tissue temperatures obtained by the implantable transponders were compared with rectal temperatures recorded by a conventional digital thermometer. Currently which of the following organizations does not include laboratory mice and rats in their oversight activities.
Rodents are commonly used to study the pathophysiological mechanisms of pain as studies in humans may be difficult to perform and ethically limited. It takes the reader through the concept of body and shell as a route to explain the variety of temperature measurements that are observed in health and disease and the interdependence between skin and core temperature in maintaining thermal stability and thermal comfort. In this chapter the nuance of body temperature is explored in the context of contemporary clinical medicine and technology. Which statement is true about a records management system for clinical assessments of rodents. It also presents information regarding the use of devices and the process for treating hypothermia. As pain cannot be directly measured in rodents many methods that quantify pain like behaviors or nociception have been developed.
Mean skin temperature while less important than core temperature is nonetheless important for at least three reasons. Should incorporate a way to flag cages of animals to be monitored within an animal housing room. And 3 the combination of core and mean skin temperatures can be used to estimate mean body. Heat sources should be modulated to a safe temperature. These behavioral methods can be divided into stimulus evoked or non stimulus evoked spontaneous nociception. The specific regimen should be developed with input form the facility veterinarian q.
A rats normal temperature ranges from 100 103f 38 39c.